Stockholders' Equity (Tables)
|
6 Months Ended |
12 Months Ended |
Jun. 30, 2017 |
Dec. 31, 2016 |
Stockholders' Equity [Abstract] |
|
|
Schedule of stock based compensation |
|
|
For the Three Months Ended June 30, |
|
|
For Six Months Ended June 30, |
|
|
|
2017 |
|
|
2016 |
|
|
2017 |
|
|
2016 |
|
Research and development |
|
$ |
76,267 |
|
|
$ |
103,537 |
|
|
$ |
142,960 |
|
|
$ |
174,744 |
|
General and administrative |
|
|
122,184 |
|
|
|
106,118 |
|
|
|
470,004 |
|
|
|
158,557 |
|
Total |
|
$ |
198,451 |
|
|
$ |
209,655 |
|
|
$ |
612,964 |
|
|
$ |
333,301 |
|
|
|
Schedule of stock option activity |
|
|
|
|
|
|
|
|
Weighted Average |
|
|
|
|
|
|
Stock Options |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2016 |
|
|
4,652,497 |
|
|
|
1,908,883 |
|
|
$ |
0.92 |
|
|
$ |
0.41 |
|
|
$ |
0.41 |
|
|
|
8.24 |
|
|
$ |
- |
|
Granted |
|
|
1,031,000 |
|
|
|
100,000 |
|
|
|
2.40 |
|
|
|
2.40 |
|
|
|
6.25 |
|
|
|
6.25 |
|
|
|
- |
|
Exercised |
|
|
(16,250 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(153,750 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – June 30, 2017 |
|
|
5,513,497 |
|
|
|
2,745,159 |
|
|
$ |
0.98 |
|
|
$ |
0.59 |
|
|
$ |
0.59 |
|
|
|
6.73 |
|
|
$ |
3,805,494 |
|
|
|
|
|
|
|
|
|
|
Weighted Average |
|
|
|
|
|
|
Stock Options |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2014 |
|
|
2,609,811 |
|
|
|
459,437 |
|
|
$ |
0.38 |
|
|
$ |
0.17 |
|
|
$ |
0.17 |
|
|
|
9.57 |
|
|
$ |
- |
|
Granted |
|
|
1,174,820 |
|
|
|
786,696 |
|
|
|
1.01 |
|
|
|
1.00 |
|
|
|
0.38 |
|
|
|
3.48 |
|
|
|
- |
|
Exercised |
|
|
(55,548 |
) |
|
|
(55,548 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(5,000 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2015 |
|
|
3,724,083 |
|
|
|
1,963,948 |
|
|
$ |
0.67 |
|
|
$ |
0.34 |
|
|
$ |
0.34 |
|
|
|
7.09 |
|
|
$ |
- |
|
Granted |
|
|
1,696,000 |
|
|
|
- |
|
|
|
1.50 |
|
|
|
- |
|
|
|
- |
|
|
|
6.25 |
|
|
|
- |
|
Exercised |
|
|
(741,100 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(26,486 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2016 |
|
|
4,652,497 |
|
|
|
1,908,883 |
|
|
$ |
0.92 |
|
|
$ |
0.41 |
|
|
$ |
0.41 |
|
|
|
8.24 |
|
|
$ |
5,561,368 |
|
|
Schedule of stock options outstanding and exercisable |
|
|
|
|
|
|
Weighted |
|
Weighted |
|
|
|
|
|
Weighted |
|
Exercise |
|
|
Number |
|
|
Average Remaining |
|
Average |
|
|
Number |
|
|
Average |
|
Price |
|
|
Outstanding |
|
|
Contractual Term |
|
Exercise Price |
|
|
Exercisable |
|
|
Exercise Price |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ |
0.05 |
|
|
|
72,876 |
|
|
4.76 years |
|
$ |
0.05 |
|
|
|
72,876 |
|
|
$ |
0.05 |
|
$ |
0.26 |
|
|
|
1,024,810 |
|
|
6.78 years |
|
$ |
0.26 |
|
|
|
978,507 |
|
|
$ |
0.26 |
|
$ |
0.73 |
|
|
|
1,475,687 |
|
|
7.38 years |
|
$ |
0.73 |
|
|
|
953,048 |
|
|
$ |
0.73 |
|
$ |
1.00 |
|
|
|
313,124 |
|
|
8.06 years |
|
$ |
1.00 |
|
|
|
166,457 |
|
|
$ |
1.00 |
|
$ |
1.10 |
|
|
|
10,000 |
|
|
8.53 years |
|
$ |
1.10 |
|
|
|
3,959 |
|
|
$ |
1.10 |
|
$ |
1.17 |
|
|
|
70,000 |
|
|
8.37 years |
|
$ |
1.17 |
|
|
|
31,875 |
|
|
$ |
1.17 |
|
$ |
1.22 |
|
|
|
125,000 |
|
|
8.60 years |
|
$ |
1.22 |
|
|
|
44,271 |
|
|
$ |
1.22 |
|
$ |
1.50 |
|
|
|
40,000 |
|
|
8.67 years |
|
$ |
1.50 |
|
|
|
13,333 |
|
|
$ |
1.50 |
|
$ |
1.55 |
|
|
|
1,456,000 |
|
|
8.69 years |
|
$ |
1.55 |
|
|
|
353,750 |
|
|
$ |
1.55 |
|
$ |
2.40 |
|
|
|
926,000 |
|
|
9.59 years |
|
$ |
2.40 |
|
|
|
127,083 |
|
|
$ |
2.40 |
|
Totals |
|
|
|
5,513,497 |
|
|
|
|
|
|
|
|
|
2,745,159 |
|
|
|
|
|
|
|
|
|
|
|
|
Weighted |
|
Weighted |
|
|
|
|
|
Weighted |
|
Exercise |
|
|
Number |
|
|
Average Remaining |
|
Average |
|
|
Number |
|
|
Average |
|
Price |
|
|
Outstanding |
|
|
Contractual Term |
|
Exercise Price |
|
|
Exercisable |
|
|
Exercise Price |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ |
0.05 |
|
|
|
72,876 |
|
|
5.25 years |
|
$ |
0.05 |
|
|
|
72,876 |
|
|
$ |
0.05 |
|
$ |
0.26 |
|
|
|
1,024,810 |
|
|
7.28 years |
|
$ |
0.26 |
|
|
|
919,296 |
|
|
$ |
0.26 |
|
$ |
0.73 |
|
|
|
1,475,687 |
|
|
7.87 years |
|
$ |
0.73 |
|
|
|
768,587 |
|
|
$ |
0.73 |
|
$ |
1.00 |
|
|
|
313,124 |
|
|
8.56 years |
|
$ |
1.00 |
|
|
|
126,457 |
|
|
$ |
1.00 |
|
$ |
1.10 |
|
|
|
10,000 |
|
|
9.02 years |
|
$ |
1.10 |
|
|
|
- |
|
|
$ |
1.10 |
|
$ |
1.17 |
|
|
|
70,000 |
|
|
8.87 years |
|
$ |
1.17 |
|
|
|
21,667 |
|
|
$ |
1.17 |
|
$ |
1.22 |
|
|
|
190,000 |
|
|
9.10 years |
|
$ |
1.22 |
|
|
|
- |
|
|
$ |
1.22 |
|
$ |
1.50 |
|
|
|
40,000 |
|
|
9.17 years |
|
$ |
1.50 |
|
|
|
- |
|
|
$ |
1.50 |
|
$ |
1.55 |
|
|
|
1,456,000 |
|
|
9.19 years |
|
$ |
1.55 |
|
|
|
- |
|
|
$ |
1.55 |
|
Totals |
|
|
|
4,652,497 |
|
|
|
|
|
|
|
|
|
1,908,883 |
|
|
|
|
|
|
Schedule of warrant activity |
|
|
|
|
|
|
|
|
|
Weighted Average |
|
|
|
|
|
|
Warrants |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2014 |
|
|
933,617 |
|
|
|
933,617 |
|
|
$ |
0.28 |
|
|
$ |
0.28 |
|
|
$ |
0.21 |
|
|
|
8.64 |
|
|
$ |
- |
|
Granted |
|
|
7,002,774 |
|
|
|
7,002,774 |
|
|
|
2.00 |
|
|
|
2.00 |
|
|
|
0.43 |
|
|
|
1.52 |
|
|
|
- |
|
Exercised |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2015 |
|
|
7,936,391 |
|
|
|
7,936,391 |
|
|
$ |
1.80 |
|
|
$ |
1.80 |
|
|
$ |
0.41 |
|
|
|
1.80 |
|
|
$ |
- |
|
Granted |
|
|
490,550 |
|
|
|
428,050 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(1,745,890 |
) |
|
|
(1,745,890 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2016 |
|
|
6,681,051 |
|
|
|
6,618,551 |
|
|
$ |
1.74 |
|
|
$ |
1.74 |
|
|
$ |
0.41 |
|
|
|
0.98 |
|
|
$ |
2,516,058 |
|
|