Stockholders' Equity (Tables)
|
9 Months Ended |
Sep. 30, 2018 |
Stockholders' Equity [Abstract] |
|
Schedule of stock-based compensation |
|
|
For the Three Months Ended September 30, |
|
|
For the Nine Months Ended September 30, |
|
|
|
2018 |
|
|
2017 |
|
|
2018 |
|
|
2017 |
|
Research and development |
|
$ |
1,188,545 |
|
|
$ |
441,629 |
|
|
$ |
2,299,934 |
|
|
$ |
584,589 |
|
General and administrative |
|
|
424,809 |
|
|
|
126,242 |
|
|
|
1,100,598 |
|
|
|
596,246 |
|
Total |
|
$ |
1,613,354 |
|
|
$ |
567,871 |
|
|
$ |
3,400,532 |
|
|
$ |
1,180,835 |
|
|
Schedule of stock option activity |
|
|
|
|
|
|
|
|
Weighted Average |
|
|
Aggregate |
|
|
|
Stock Options |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Intrinsic |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Value |
|
Balance – December 31, 2017 |
|
|
5,691,414 |
|
|
|
3,124,941 |
|
|
$ |
1.16 |
|
|
$ |
0.73 |
|
|
$ |
0.73 |
|
|
|
6.87 |
|
|
$ |
- |
|
Granted |
|
|
758,000 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(563,121 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(360,459 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – September 30, 2018 |
|
|
5,525,834 |
|
|
|
3,870,451 |
|
|
$ |
2.06 |
|
|
$ |
1.28 |
|
|
$ |
1.28 |
|
|
|
5.74 |
|
|
$ |
14,150,427 |
|
|
Schedule of stock options outstanding and exercisable |
|
|
|
|
|
|
Weighted |
|
Weighted |
|
|
|
|
Exercise |
|
|
Number |
|
|
Average Remaining |
|
Average |
|
|
Number |
|
Price |
|
|
Outstanding |
|
|
Contractual Term |
|
Exercise Price |
|
|
Exercisable |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ |
0.05 |
|
|
|
52,876 |
|
|
3.51 years |
|
$ |
0.05 |
|
|
|
52,876 |
|
$ |
0.26 |
|
|
|
915,497 |
|
|
5.53 years |
|
$ |
0.26 |
|
|
|
915,497 |
|
$ |
0.73 |
|
|
|
1,131,691 |
|
|
6.13 years |
|
$ |
0.73 |
|
|
|
1,080,621 |
|
$ |
1.00 |
|
|
|
237,124 |
|
|
6.81 years |
|
$ |
1.00 |
|
|
|
190,457 |
|
$ |
1.10 |
|
|
|
8,000 |
|
|
7.27 years |
|
$ |
1.10 |
|
|
|
5,083 |
|
$ |
1.17 |
|
|
|
20,772 |
|
|
7.12 years |
|
$ |
1.17 |
|
|
|
4,522 |
|
$ |
1.22 |
|
|
|
46,874 |
|
|
7.35 years |
|
$ |
1.22 |
|
|
|
5,207 |
|
$ |
1.50 |
|
|
|
28,000 |
|
|
7.42 years |
|
$ |
1.50 |
|
|
|
13,833 |
|
$ |
1.55 |
|
|
|
1,132,000 |
|
|
7.44 years |
|
$ |
1.55 |
|
|
|
707,500 |
|
$ |
2.02 |
|
|
|
85,000 |
|
|
8.86 years |
|
$ |
2.02 |
|
|
|
52,500 |
|
$ |
2.40 |
|
|
|
915,000 |
|
|
8.34 years |
|
$ |
2.40 |
|
|
|
540,583 |
|
$ |
4.60 |
|
|
|
200,000 |
|
|
9.19 years |
|
$ |
4.60 |
|
|
|
37,500 |
|
$ |
5.30 |
|
|
|
275,000 |
|
|
9.49 years |
|
$ |
5.30 |
|
|
|
120,521 |
|
$ |
6.04 |
|
|
|
278,000 |
|
|
9.64 years |
|
$ |
6.04 |
|
|
|
131,250 |
|
$ |
8.86 |
|
|
|
200,000 |
|
|
9.69 years |
|
$ |
8.86 |
|
|
|
12,501 |
|
Totals |
|
|
|
5,525,834 |
|
|
|
|
|
|
|
|
|
3,870,451 |
|
|
Schedule of warrants activity |
|
|
|
|
|
|
|
|
Weighted Average |
|
|
Aggregate |
|
|
|
Warrants |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Intrinsic |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Value |
|
Balance – December 31, 2017 |
|
|
4,533,020 |
|
|
|
4,517,395 |
|
|
$ |
1.85 |
|
|
$ |
1.85 |
|
|
$ |
1.00 |
|
|
|
3.21 |
|
|
$ |
- |
|
Granted |
|
|
780,500 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(349,315 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – September 30, 2018 |
|
|
4,964,205 |
|
|
|
4,964,205 |
|
|
$ |
2.39 |
|
|
$ |
2.39 |
|
|
$ |
1.14 |
|
|
|
2.52 |
|
|
$ |
10,325,281 |
|
|