Stockholders' Equity (Tables)
|
12 Months Ended |
Dec. 31, 2018 |
Stockholders' Equity Note [Abstract] |
|
Schedule of stock-based compensation |
|
|
For
the Years Ended December 31, |
|
|
|
2018 |
|
|
2017 |
|
Research and development |
|
$ |
2,583,251 |
|
|
$ |
884,032 |
|
General and administrative |
|
|
1,735,742 |
|
|
|
749,453 |
|
Total |
|
$ |
4,318,993 |
|
|
$ |
1,633,485 |
|
|
Schedule of stock option activity |
|
|
|
|
|
|
|
|
Weighted
Average |
|
|
|
|
|
|
Stock
Options |
|
|
Exercise
Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2016 |
|
|
4,652,497 |
|
|
|
1,908,883 |
|
|
$ |
0.92 |
|
|
$ |
0.41 |
|
|
$ |
0.41 |
|
|
|
8.24 |
|
|
$ |
- |
|
Granted |
|
|
1,316,000 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(123,333 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(153,750 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2017 |
|
|
5,691,414 |
|
|
|
3,124,941 |
|
|
$ |
1.16 |
|
|
$ |
0.73 |
|
|
$ |
0.73 |
|
|
|
6.87 |
|
|
$ |
- |
|
Granted |
|
|
860,000 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(602,533 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(460,599 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2018 |
|
|
5,488,282 |
|
|
|
4,384,294 |
|
|
$ |
2.10 |
|
|
$ |
1.32 |
|
|
$ |
1.32 |
|
|
|
5.80 |
|
|
$ |
8,437,330 |
|
|
Schedule of stock options outstanding and exercisable |
Grant
Price |
|
|
Weighted
Average |
|
|
Total
|
|
|
Number |
|
Weighted Average
Remaining |
From |
|
|
To |
|
|
Exercise
Price |
|
|
Outstanding |
|
|
Exercisable |
|
Contractual
Term |
$ |
0.05 |
|
|
$ |
2.02 |
|
|
$ |
0.90 |
|
|
|
3,533,282 |
|
|
3,432,344 |
|
6.21 years |
$ |
2.40 |
|
|
$ |
4.60 |
|
|
$ |
2.87 |
|
|
|
1,202,000 |
|
|
627,208 |
|
8.38 years |
$ |
5.30 |
|
|
$ |
8.86 |
|
|
$ |
6.52 |
|
|
|
753,000 |
|
|
324,742 |
|
9.35
years |
|
|
|
|
|
|
|
|
|
Totals |
|
|
|
5,488,282 |
|
|
4,384,294 |
|
|
|
Schedule of warrants activity |
|
|
|
|
|
|
|
|
Weighted
Average |
|
|
|
|
|
|
Warrants |
|
|
Exercise
Price |
|
|
Fair
Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life
(Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2016 |
|
|
6,681,051 |
|
|
|
6,618,551 |
|
|
$ |
1.74 |
|
|
$ |
1.74 |
|
|
$ |
0.41 |
|
|
|
0.98 |
|
|
$ |
- |
|
Granted |
|
|
3,618,053 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(1,070,238 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(4,695,846 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2017 |
|
|
4,533,020 |
|
|
|
4,517,395 |
|
|
$ |
1.85 |
|
|
$ |
1.85 |
|
|
$ |
1.00 |
|
|
|
3.21 |
|
|
$ |
- |
|
Granted |
|
|
780,500 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(349,315 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2018 |
|
|
4,964,205 |
|
|
|
4,964,205 |
|
|
$ |
2.39 |
|
|
$ |
2.39 |
|
|
$ |
1.14 |
|
|
|
2.27 |
|
|
$ |
5,304,835 |
|
|