Stockholders' Equity (Tables)
|
12 Months Ended |
Dec. 31, 2019 |
Stockholders' Equity Note [Abstract] |
|
Schedule of stock-based compensation |
|
|
For
the Years Ended
December 31, |
|
|
|
2019 |
|
|
2018 |
|
Research
and development |
|
$ |
915,075 |
|
|
$ |
2,583,251 |
|
General
and administrative |
|
|
1,694,295 |
|
|
|
1,735,742 |
|
Total |
|
$ |
2,609,370 |
|
|
$ |
4,318,993 |
|
|
Schedule of stock option activity |
|
|
|
|
|
|
|
|
Weighted
Average |
|
|
|
|
|
|
Stock
Options |
|
|
Exercise
Price |
|
|
Fair
Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance
– December 31, 2017 |
|
|
5,691,414 |
|
|
|
3,124,941 |
|
|
$ |
1.16 |
|
|
$ |
0.73 |
|
|
$ |
0.73 |
|
|
|
6.87 |
|
|
$ |
- |
|
Granted |
|
|
860,000 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(602,533 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(460,599 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance
– December 31, 2018 |
|
|
5,488,282 |
|
|
|
4,384,294 |
|
|
$ |
2.10 |
|
|
$ |
1.32 |
|
|
$ |
1.32 |
|
|
|
5.80 |
|
|
$ |
- |
|
Granted |
|
|
2,779,000 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(441,210 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(193,714 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance
– December 31, 2019 |
|
|
7,632,358 |
|
|
|
4,542,144 |
|
|
$ |
2.21 |
|
|
$ |
1.57 |
|
|
$ |
1.57 |
|
|
|
6.44 |
|
|
$ |
2,364,422 |
|
|
Schedule of stock options outstanding and exercisable |
Grant
Price |
|
|
Weighted Average |
|
|
Total |
|
|
Number |
|
|
Weighted
Average
Remaining Contractual |
|
From |
|
|
To |
|
|
Exercise
Price |
|
|
Outstanding |
|
|
Exercisable
|
|
|
Term |
|
$ |
0.05 |
|
|
$ |
2.02 |
|
|
$ |
0.89 |
|
|
|
3,290,357 |
|
|
|
3,086,190 |
|
|
|
4.32
years |
|
$ |
2.40 |
|
|
$ |
4.60 |
|
|
$ |
2.47 |
|
|
|
3,649,001 |
|
|
|
998,021 |
|
|
|
8.64
years |
|
$ |
5.30 |
|
|
$ |
8.86 |
|
|
$ |
6.62 |
|
|
|
693,000 |
|
|
|
457,933 |
|
|
|
8.36
years |
|
|
|
|
|
|
|
|
|
|
Totals |
|
|
|
7,632,358 |
|
|
|
4,542,144 |
|
|
|
|
|
|
Schedule of warrants activity |
|
|
|
|
|
|
|
|
Weighted Average |
|
|
|
|
|
|
Warrants |
|
|
Exercise Price |
|
|
Fair Value |
|
|
Contractual |
|
|
Aggregate |
|
|
|
Outstanding |
|
|
Exercisable |
|
|
Outstanding |
|
|
Exercisable |
|
|
Vested |
|
|
Life (Years) |
|
|
Intrinsic Value |
|
Balance – December 31, 2017 |
|
|
4,533,020 |
|
|
|
4,517,395 |
|
|
$ |
1.85 |
|
|
$ |
1.85 |
|
|
$ |
1.00 |
|
|
|
3.21 |
|
|
$ |
- |
|
Granted |
|
|
780,500 |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(349,315 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2018 |
|
|
4,964,205 |
|
|
|
4,964,205 |
|
|
$ |
2.39 |
|
|
$ |
2.39 |
|
|
$ |
1.14 |
|
|
|
2.27 |
|
|
$ |
- |
|
Granted |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised |
|
|
(50,000 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Cancelled |
|
|
(6,982 |
) |
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Balance – December 31, 2019 |
|
|
4,907,223 |
|
|
|
4,907,223 |
|
|
$ |
2.40 |
|
|
$ |
2.40 |
|
|
$ |
1.11 |
|
|
|
1.55 |
|
|
$ |
1,077,594 |
|
|